Global Warming and Climate Change Essay - 1057 Words

Global Warming, much of what does or does not happen forty years from now rests on our actions or inactions taken between now and then. The crucial question is whether we should pour all our resources into mitigation – reducing our carbon emissions. According to scientists who study the climate there are other environmental problems; â€Å"we now face a global crises in land use and agriculture that could undermine the health, security, and sustainability of our civilization†. Rather than worry too much about emissions, we should accept the world is going to get warmer anyway and adapt to global warming by building better flood defenses and developing drought resistant crops. We cannot dispute that automobiles, factories, and power plants,†¦show more content†¦It was the strongest in 32 years. Then the wettest fifteen days in Iowa history began on May 29. Global food prices soared as farm fields in America’s top state producer of corn and soybeans wash away. Leaving two million acres of the most effective farmland in the country wounded in such a way as to impair its usefulness. Impacting a thriving agricultural economy. In 2009 alone, drought cost farmers $14 billion worldwide. Eighty-five percent of the U.S. corn crop is affected by drought stress at some time during the growing season each year, and just four days of severe drought stress during the peak of summer can cut yields in half. â€Å"If this isn’t enough, we must also address the massive environmental impacts of our current agricultural practices, which new evidence indicates rival the impacts of climate change.† â€Å"Consider the following: ecosystem degradation, fresh water decline, and widespread pollution.† So, what are the solutions to the global crisis? First we must understand the unsettling challenge of nearly doubling agriculture production to meet the demands of the estimated 9 billion people expected by 2050. Success in this undertaking will require new and sustained levels of innovation, such as improvements in drought tolerance, to increase productivity of the global food supply without increasing the stress upon our natural resources of the environment. Our goal should be that all people, at allShow MoreRelatedGlobal Warming And Climate Change974 Words   |  4 Pagesabout global warming, whether it is true or false. Is there evidence to prove that global warming has impacted the climate due to the rise in the earth’s temperature? Climate change is a problem that is worldwide that should be reviewed. The rise in the earth’s temperature has caused some impact to the weather and climate changes to many places worldwide. This rise in temperature has the potential of causing drastic changes to the earth in many ways. It is time to view the global warming concernsRead MoreClimate Change Of Global Warming924 Words   |  4 Pages Figure 0.1 shows the different effects of global warming. Global warming is the warming of our planet at an extreme rate. The Earth’s climate has warmed by 7.8OC since 1880. (Quick facts about science, 2015). What causes global warming? The cause of global warming is the carbon dioxide. This acts like a blanket. Protecting the earth, and heating the earth. Sun rays would normally bounce around the earth, but with the blanket, the sun rays heat the blanket which heats the earth. (Petersen ScienceRead MoreGlobal Warming And Climate Change1398 Words   |  6 Pages Global warming and climate change have been frequent topics of discussion over the past several years. Although people tend to focus on the politics, it is important to look past the media aspects of it into the cold hard facts of what our Earth is currently experiencing, and what has caused it in the first place. The cause of climate change includes natural causes, but human causes are what is generating such a rapid global temperature change. It’s time that the ways in which humanity affectsRead MoreClimate Change And Global Warming1060 Words   |  5 PagesClimate change (Klaus) 1000 The terms â€Å"global warming†, â€Å"climate change† or â€Å"greenhouse effect† have become more than just parts of the popular lexicon as they rather are subject of public discussions, scientific research or political debates. Despite the popularity and the ubiquity of these terms, the public’s theoretical and conceptual understanding of them and their causal relations is often based on superficial knowledge and buzzwords or caricatures outlined and depicted in several popular mediaRead MoreClimate Change : Global Warming1194 Words   |  5 PagesDonya Curtis April 19, 2017 English 1001-rough draft Global Warming Global warming is one facet of the broader term climate change. It is the increase in the average temperature of the Earth s surface air and oceans from the mid 20th century and the projected continuation. The Global warming is primarily the consequence of building up greenhouse gasses in the atmosphere. Emission rates for most important anthropogenic greenhouse gas, CO2, have increased 120 fold in the past 140 years. WhileRead MoreClimate Change and Global Warming1074 Words   |  5 PagesClimate change and Global Warming are out of control. This means that, no matter what policies, processes or actions are implemented, the Earth as we know it will never be the same again. There is significant evidence to support this hypothesis. The dilemma becomes whether we can limit the damage and adapt to a new status quo or not. Rising sea levels and the damage caused by this phenomenon has irreversible impacts on coastlines worldwide. Damage to sensitive reef systems cannot be fixed. This alsoRead MoreClimate Change And Global Warming1022 Words   |  5 PagesWhat = Climate Change Who = Emma, Aoife, Julia, Rachael, Mariah and Cà ©line What is it? Climate Change is a change in the demographic distribution of weather patterns, and related change in oceans, land surfaces and ice sheets, happening over time scales of decades or longer. It’s the world’s greatest threat. Climate change is the change in temperature over a period of time. It involves the greenhouse effect and global warming. Where is it? It is an issue affecting everyone everywhere. ClimateRead MoreClimate Change And Global Warming1474 Words   |  6 Pagesphenomenon, known as â€Å"smog† became an often daily occurrence in big, urbanized cites across the globe. Also, Al Gore’s book, An Inconvenient Truth, popularized the issue of climate change and global warming as a result of the damage that the modern world has done to the atmosphere. He noted that people resist the facts about climate change due to the inconvenience of changing their lifestyles. But, uninhibited industrialization of several countries has led to intense modernization and revolution of theRead MoreClimate Change And Global Warming928 Words   |  4 PagesThis paper will discuss climate change and global warming on the economy. The paper also gives a description on climate change and global warming. As well as what it hold for future business owners. It will also discuss what the government is doing about climate change/global warming. Climate change is a long-term shift in the statistics of the weather (including its averages). For example, it could show up as a change in climate normal (expected average values for temperature and precipitation)Read MoreClimate Change And Global Warming1630 Words   |  7 PagesClimate Related Threats Global warming will lead to uncontrollable devastation such as famine, war, and economic instability. Climate change will accelerate the dislocation of hundreds of millions of people and the extinction of many species. The negative effects of climate change are obvious on every continent. Professor Le Quere, director of the Tyndall Centre for Climate Change Research at the University of East Anglia said, The human influence on climate change is clear. The atmosphere and

Is Canadian Culture Doomed to Become American Essay

Is Canadian Culture Doomed to Become American? As Alvin Toffler once said, â€Å"The wider any culture is spread, the thinner it gets†1. Such holds true for the American culture, which is not only a dominating factor in its own internal market and known domestically but also a dictating force in countries around the world on the global scale, and the first on their list – Canada. This issue of cultural imperialism is touched upon by Gaà «tan Tremblay in his article, â€Å"Is Quebec Culture Doomed to Become American?† Although Tremblay talks about the American culture’s influence on Canada as a whole, his main concern in this article is Quebec, which is in a separate league than the rest of Canada due to its different linguistics. Tremblay†¦show more content†¦They feel as if there is â€Å"a real threat of cultural invasion†5 from the American culture. Tremblay uses some significant points to establish his argument and prove his position and opinion. The first issue he raises is the presence of American programs on Quebec television, where he mentions that about one third of the total television supply is of foreign origin mainly American, which is not so bad but he does reveal that the presence of foreign products is much higher in Canada compared to the United States. He also states that during the evenings, between six o’clock and midnight, the situation is even better because â€Å"the proportion of Canadian content attains 73%†6. He mentions that the French-language television stations for the most part, respect the â€Å"Commission’s regulatory quota fixing a 60% minimum for Canadian content during prime time†7. The part that Canadians should be concerned with is the area of entertainment, particularly drama programming such as series, films and cartoons. He indicates that the percentage of drama p rogramming broadcast produced locally by francophone Quebecois television stations decreased from 16.9% in 1982, to less than 10% in 1989, which is quite a significant plunge. An entertainment sector that is really vulnerable to American culture is the production of films. In 1990, Tremblay states that according to The Social Communication Board, compared to 55% American films, there wereShow MoreRelated The American Cultural Invasion of Canada Essay1298 Words   |  6 PagesThe American Cultural Invasion of Canada â€Å" Canada s national obsession seems to be its own identity.† For many years Canada has feared the increasing influence of its North American neighbors on its culture - the United States . It has become a matter of growing concern for the people of power and influence in Canada to maintain their separate cultural identity and to promote their own cultural norms. Gaetan Tremblay presents his views on this topic and does this from the perspective of a personRead MoreThe Uncertain Future Of Quebec Culture1335 Words   |  6 PagesFuture of Quebec Culture Gaetan Tremblay, a professor of communications at the University of Quebec at Montreal and deputy manager of the Group of research on cultural industries and social computerization (GRICIS), is a leading researcher for public policies in the field of communications. Tremblay is an advocate of public policy that defends against cultural imperialism by countries such as the United States . In particular, Tremblay studies the effects of the media on culture in Canada especiallyRead MoreDiscuss One of the Literary Works on the Course Reading List. Looking at the Settings, the Characters, and/or the Themes of the Book, What Does It Tell You About Canada and Canadian Culture? Maria Chapdelaine, by Louis Hà ©mon,1652 Words   |  7 Pagesbook, what does it tell you about Canada and Canadian culture? Maria Chapdelaine, by Louis Hà ©mon, Maria Chapdelaine, written by French author Louis Hà ©mon, represents Canadian identity, its cultural and social aspects. Even though the book seems quite easy to read, the story is, in fact, pretty complex to comprehend - it is truly philosophical, there are many ways to analyze it. In my opinion, book introduces north Canadians lifestyle and difficulties they face,Read MoreEnglish Is An International Business Language1399 Words   |  6 PagesThe surest factor in accelerating the development of a universal way of life is proved by the spread of English. Language - the great agent of homogenization, it is the wave on which culture is transmitted. If English becomes the main language of communication, the consequences are obvious: culture of English-speaking countries will be dominant in the world. English is the first universal global language. Although there may be as many people who speak different dialects of Chinese language, as wellRead MoreThe Impact Of Immigration On The United States And Canada Essay1552 Words   |  7 PagesChapter One: Introduction to Investigation Immigration to North American nations has been a staple process for countries like the United States and Canada. Without immigrants, these two nations would not have become as large and successful as they are today. However, easy and encouraged immigration has not always been a constant for these two countries. Throughout the centuries, there have been issues and disputes over immigration for particular ethnicities and groups of people which continue evenRead MoreCanada and Quebecs Conflict Essay example1971 Words   |  8 Pagesconfederation of 1867 to the Supreme court judgement on the secession of Quebec in 1998. Quebec faces several challenges in terms of constitutional relations with the rest of Canada. Quebec is seeking a special status to preserve and protect its culture and language, while the rest of English-speaking Canada accepts the view of provincial equality. There have been attempts to recognize Quebecs concerns through constitutional amendments, but these attempts h ave not lived up to Quebecs expectationsRead MoreHistory Grade 10 Exam Review6476 Words   |  26 PagesConservative * William Lyon Mackenzie King: 1921- 1926, 1926- 1930, 1935- 1948 * Liberal * Independence of Canada in foreign policies * Richard Bennett: 1930- 1935 * Conservative * Create Bank of Canada, 1934 * Canadian Wheat Board, 1935 * Unemployment Benefits, 1935 * Maurice Duplessis: 1936- 1939, 1944- 1959. * Union Nationale * Fleur- de -Lys * Dark Period in Quebecs history * William Aberhart (Premier of Alberta): 1935- 1943Read MoreWestern Culture in Two Gemanies2679 Words   |  11 Pagesfundamental difference in political ideals of two of the great nation at the time, the United States of American, and the Soviet Union. Throughout the life spans of these two nations one of the largest concern were the youth; as the future population of both nations, it would be on the shoulders of the youth that the countries ideal would be preserved or forgotten. During this time the influence of Western culture was permeating throughout most of the world, and both Germanies were not excluded. ThroughoutRead MoreWomen, Ageism, and Poverty in Canada2779 Words   |  12 Pagesas less worthy. This is because they don`t have the time, energy or appearance to continue contributing to society. In Amy J. C. Cuddy’s chapter in Ageism, she discusses the stereotyping of old age as being weak and frail (Nelson, p.4). North American culture promotes youth and beaut y, and the aged appear to have neither the stamina nor the understanding of the young because of their aged appearance. Diversiton states that by emphasizing a youthful physical appearance, it demeans the older woman (http://wwwRead MoreExploring Objectification Theory Through Media Output and Seduction Masters2168 Words   |  9 PagesThe United States was founded on principles of liberty, justice, and equality for all. In fact, the United States has gone to great lengths to uphold these principles for all. Except for Jews, Asians, African Americans and every other minority. Especially Women. The ‘Other Gender’ has been looked down upon since the conception of man. Previously, it was directed in the stereotype of male superiority, but now a far greater threat to women’s equal rights is emerging. The media has taken to idolizing

Introduction of Johnson Johnson Free Essays

string(169) " business is Our Credo, a deeply held set of values that have served as the strategic and moral compass for generations of Johnson Johnson leaders and employees\." Introduction of Johnson Johnson As a consumer, you’re familiar with our name. The rich heritage brands from our operating companies have helped people around the world, and chances are your own family has trusted our products for generations. Johnson Johnson is the world’s most comprehensive and broadly based manufacturer of health care products in the industry. We will write a custom essay sample on Introduction of Johnson Johnson or any similar topic only for you Order Now Our products touch the lives of nearly a billion people every day. Our operating companies around the world compete in consumer, pharmaceutical, and medical devices and diagnostics markets. With approximately 120,000 employees working in more than 250 companies in 57 countries, our Family of Companies has the skills and resources to tackle the world’s most pressing health issues. Few companies have the consistent track record of public trust, annual sales increases, double-digit earnings increases, and steady dividend increases of Johnson Johnson. Working together across our various business segments, we believe that we can accelerate growth through a dedicated focus on the intersection of our existing capabilities, customer need, and emerging trends. Because of our wide-ranging technological expertise and global presence, cross-business collaborations provide an enormous opportunity to address unmet health care needs and to enhance competitive advantage for our Family of Companies. They include In the coming decades, a significant portion of our growth will come from the Asia-Pacific, Latin America, and Europe/Middle East/Africa global regions, through Success in these markets requires an understanding of local cultures derived only from local experience. By sourcing top business and technology employment candidates for positions in their home countries, we can build organizations, facilities, and product marketing systems that respond to local needs. Rallying around the imperative of flawless execution helps our employees around the world Innovations within each of these product platforms take shape through a number of avenues, including Today, and for most of our history, our success is driven by our commitment to principles that are ingrained in our culture. These principles provide continuity in our approach to business opportunities, but they also stablish consistencies in our management style. Our key strengths serve as  a springboard for accelerating our growth and our contribution to human health around the world. Johnson Johnson is committed to building on our knowledge and experience in order to take the lead in a rapidly evolving health care marketplace. Commitment to the promise of science and technology helps us  pro duce innovative products and seek cures for diseases. Collaboration across our businesses and franchises expands competitive advantage and helps us address unmet medical needs. Pariticipation in  global markets—many with substantial unmet medical needs—offers tremendous potential. Recognition of  the responsibility inherent in our health care mission compels us to maintain the highest quality and on-time delivery. Explore Our Expansive Business Strategy A wide focus on health care As a consumer, you’re familiar with our name. The rich heritage brands from our operating companies have helped people around the world, and chances are your own family has trusted our products for generations. Johnson Johnson is the world’s most comprehensive and broadly based manufacturer of health care products in the industry. Our products touch the lives of nearly a billion people every day. Our operating companies around the world compete in consumer, pharmaceutical, and medical devices and diagnostics markets. With approximately 120,000 employees working in more than 250 companies in 57 countries, our Family of Companies has the skills and resources to tackle the world’s most pressing health issues. Our strategic principles Few companies have the consistent track record of public trust, annual sales increases, double-digit earnings increases, and steady dividend increases of Johnson Johnson. Our strategic principles define our management approach and help us build on the strengths of our heritage. Our approach to a converging health care market Johnson Johnson recognizes that leveraging our world-class talent with cutting-edge technology has the potential to create innovative, effective product solutions and a novel approach to holistic patient care. Our vision for growth Working together across our various business segments, we believe that we can accelerate growth through a dedicated focus on the intersection of our existing capabilities, customer need, and emerging trends. Our growth imperatives and our commitment to developing capable, values-based leaders define our vision to rise to a new level of strength. Our strategic approach Few companies have the public trust in the record sales growth, double-digit increases in earnings, as well as Johnson Johnson’s steady increase in dividend. Our strategic approach to determine our management approach and help us to consolidate our traditional strengths. The convergence of our approach medical market Johnson Johnson acknowledged that the use and cutting of our world-class talent, advanced technology, it is possible to create innovative, cost effective product solutions and a comprehensive new method for patient care. Our healthy growth Our work in various business fields, we believe we can accelerate our existing capabilities through a dedicated focus on the junction growth, customer needs, emerging trends. Our growth needs and we are committed to developing skills, values-based leaders set out our objectives, creating a new power level. Johnson Johnson is a company of enduring strength. We’ve been privileged to play a role in helping millions of people the world over be well and stay well through more than a century of change. As the science of human health and well-being has grown, we’ve been able to grow along with it. Even more important, we’ve helped shape and define what health and well-being means in every day lives. Our products, services, ideas and giving now touch the lives of at least one billion people everyday. We credit our strength and endurance to a consistent approach to managing our business, and to the character of our people. We are guided in everything we do by Our Credo, a management document authored more than 60 years ago by Robert Wood Johnson, former chairman from 1932 to 1963, and by four strategic principles. Our Credo: Our Guiding Philosophy The overarching philosophy that guides our business is Our Credo, a deeply held set of values that have served as the strategic and moral compass for generations of Johnson Johnson leaders and employees. You read "Introduction of Johnson Johnson" in category "Papers" Above all, Our Credo challenges us to put the needs and well-being of the people we serve first. It also speaks to the responsibilities we have to our employees, to the communities in which we live and work and the world community, and to our shareholders. We believe Our Credo is a blueprint for long-term growth and sustainability that’s as relevant today as when it was written Our Credo Values Broadly Based in Human Health Being broadly based gives us a number of advantages. Our more than 250 operating companies have a local window into emerging customer needs, scientific developments, and technologies throughout the world. We turn those insights into innovative new products and sometimes whole new businesses. It allows us to transfer scientific breakthroughs, marketing insights and manufacturing expertise easily across the full range of our businesses. This broad base has helped us bring more science to the consumer health products that people use every day. To see the breadth of the Johnson Johnson companies throughout the world, explore the map. A Decentralized Management Approach We are big and we are small all at once. Each of our operating companies functions as its own small business. They are strongly entrepreneurial in character, and they know that their success depends on anticipating customers’ needs and delivering meaningful, high-quality solutions. While our people operate in a small-company setting, they also have access to the know-how and resources of a Fortune 50 company. It’s like having dozens of strategic partners at their fingertips. Explore the map to find out more about our companies throughout the world. Managed for the Long Term We focus on the fundamentals of our business, and manage with future generations in mind. While we keep our eye on social and scientific trends, we make sure our companies balance the short-term and the long-term in their strategic planning. We invest in promising new businesses while maintaining leadership positions in high growth businesses. We are focused on sustainability, and constantly review key economic, environmental, and employee health and safety indicators to ensure we are on the right path. This past year we established an internal innovation fund to keep us at the leading edge of transforming health and well-being. People and Values People and values are Johnson Johnson’s greatest assets. We know that every invention, every product, and every breakthrough we’ve brought to human health and well-being has been powered by people. Our people strive to make a difference. We believe the shared values embodied in Our Credo help us attract and keep the most talented values-driven people in the world. Our Credo Values | | | |The values that guide our decision making are spelled out in Our Credo. Put simply, Our Credo challenges us to put the | | |needs and well-being of the people we serve first. | | | | | |Robert Wood Johnson, former chairman from 1932 to 1963 and a member of the Company’s founding family, crafted Our Credo | | |himself in 1943, just before Johnson   became a publicly traded company. This was long before anyone ever heard the| | |term â€Å"corporate social responsibility. † Our Credo is more than just a moral compass. We believe it’s a recipe for business | | |success. The fact that Johnson   is one of only a handful of companies that have flourished through more than a | | |century of change is proof of that. | | | | Developing markets Growth in Developing and Underserved Markets In the coming decades, a significant portion of our growth will come from the Asia-Pacific, Latin America, and Europe/Middle East/Africa global regions, through †¢ Product marketing †¢ Innovative manufacturing †¢ Product development †¢ Leadership development activities Success in these markets requires an understanding of local cultures derived only from local experience. By sourcing top business and technology employment candidates for positions in their home countries, we can build organizations, facilities, and product marketing systems that respond to local needs. Established in 2008, one of the tasks of the Johnson Johnson Office of Strategy and Growth is to identify new growth and strategic opportunities in developing and underserved markets that have the potential to make a significant impact on human health. These opportunities are separate from those being currently pursued by our existing business segments. The Johnson Johnson International Recruitment Development program is a major component of our global success. By developing future leaders within our international businesses, we build businesses that are better aligned with the pressing health care needs of the regions in which they operate. Our decentralized management structure ensures that Johnson Johnson operations in countries across the world are run locally, with an emphasis on adapting our products and facilities to local cultures, customs, and economic vitality. Growth is driven from within these regions, rather than from afar. Our Heritage Building on the Strengths of Our Heritage Remaining true to the principles that made us strong Today, and for most of our history, our success is driven by our commitment to principles that are ingrained in our culture. These principles provide continuity in our approach to business opportunities, but they also establish consistencies in our management style. Our guiding principles are †¢ Adherence to the principles of Our Credo †¢ A broad base in human health care †¢ Commitment to decentralized management Emphasis on managing the business for the long term †¢ Dedication to people and values While Johnson Johnson is dedicated to Our Credo, which have historically guided our business, our employees, and our culture, we also use these values and beliefs to guide our strategies for the future in a rapidly converging health care marketplace. Our dedication to personal and professional gro wth among our employees, as well as an emphasis on developing new technologies to meet the needs of people around the world, positions Johnson Johnson as a global leader in the 21st century. Flawless Execution Rallying around the imperative of flawless execution helps our employees around the world †¢ Maintain the highest quality and on-time delivery of the products, projects, and processes for which they share responsibility †¢ Display vision, planning, and the ability to adapt to a changing environment †¢ Become better prepared to help us reach our goals in human health care †¢ Develop the discipline that makes tools such as process excellence, shared best practices, and review of process metrics an important part of our operating culture Cross-business Collaborations Because of our wide-ranging technological expertise and global presence, cross-business collaborations provide an enormous opportunity to address unmet health care needs and to enhance competitive advantage for our Family of Companies. They include Collaborations initiated to identify and develop innovative products Grouped purchasing agreements, shared best practices, cooperative talent acquisition and development, and shared research initiatives, undertaken to improve overall performance Their success is due, in part, to strong trust-based relationships. Commitment to the values expressed in Our Credo helps employees of Johnson Johnson companies demonstrate skill and effectiveness as they establish relationships with colleagues worldwide. The decentralized corporate structure within Johnson Johnson, when applied to innovation and business growth, results in different people with different skills, thoughts, and ideas coming together and collaborating to develop products and technologies to advance the standard of health care and satisfy unmet medical needs of patients around the world. Innovative Product Solutions Our opportunities for innovation span a range of product solution platforms that cross our consumer, pharmaceutical, and medical devices and diagnostics businesses: |Anti-infectives |Neurology | |Antifungal |Nutritionals | |Audiology |Oncology | |Cardiovascular |Oral care | |Central nervous system |Orthopaedics | |Dental |Pain and inflammation | |Diagnostics |Patient monitoring | |Dialysis |Respiratory | |Gastrointestinals |Skin care | |Hematology |Surgical instruments | |IV/vascular access |Urology | |Imaging |Vision care | |Immune-mediated inflammatory disorders Women’s health | |Needles and sutures |Wound care | Innovations within each of these product platforms take shape through a number of avenues, including: Aggressive investment in research and development To ensure our continued growth, we make a vigorous commitment to research and development in all business segments. Our RD network is strong and well-equipped, with substantial annual investments. Through wo rld-class research facilities, highly productive small team settings, and sound scientific methods, we build a pipeline and patent estate that match the breadth of our product platforms. Focus on new convergence in the marketplace Our strong commitment to RD, as well as our focus on new technologies, has positioned Johnson Johnson as a market leader ready to capitalize on the rapidly evolving health care landscape. As the marketplace sees a new and steady convergence between technology, products, and services, we see ourselves as uniquely positioned to meet the challenges and opportunities that are emerging. Extensive collaboration and strategic alliances Our broad base in health care offers our companies a unique source of innovative product solutoins: Internal collaborations both within and across business segments. Experts within specific product platforms extend their impact as they identify synergies and establish collaborative development relationships with colleagues throughout our Family of Companies. The ability to work across company boundaries enables true collaborative innovation, and sets the stage for important health care breakthroughs in the future. Additionally, each year, Johnson Johnson companies enter into hundreds of strategic alliances. These alliances combine the  unique strengths of external partners, which, when combined  with those of our businesses, build value for customers. Selective licensing and acquisition We proactively search for innovations from outside our organizations as well. Our conscientious approach to assessing licensing and acquisition opportunities has helped us expand this important source of growth Advancing to a New Level of Strength Accelerating growth by excelling as leaders Our key strengths serve as a springboard for accelerating our growth and our contribution to human health around the world. Johnson Johnson is committed to building on our knowledge and experience in order to take the lead in a rapidly evolving health care marketplace. Our pursuit is grounded in four growth imperatives: Innovative product solutions – Commitment to the promise of science and technology helps us produce innovative products and seek cures for diseases. Cross-business collaborations – Collaboration across our businesses and franchises expands competitive advantage and helps us address unmet medical needs. Growth in developing and underserved markets – Pariticipation in global markets—many with substantial unmet medical needs—offers tremendous potential. †¢ Flawless execution – Recognition of the responsibility inherent in our health care mission compels us to maintain the highest qu quality and on-time delivery. Johnson Johnson companies have the freedom to develop customized strategies that best contribute to their own growth as well as to the fulfillment of our global business strategy. In this way, our small-company environment contributes directly and uniquely to our big-company impact. Developing capable, values-based leaders Much of our success is the result of skilled leaders who have made smart choices over the years. Johnson Johnson companies rely on the ongoing development of leaders who †¢ Demonstrate integrity, passion, and the ability to set a vision and inspire organizations †¢ Create and value stimulating environments, learning and growth opportunities, and collaborative settings †¢ Guide business growth †¢ Champion adherence to the values of Our Credo Looking to the future, we are placing more emphasis than ever on the attraction, acquisition, and development of capable, values-based leaders. The convergence of technology with talent in our organization opens up new doors for our employees to facilitate exciting innovations across many platforms. Our Global Leadership Profile serves as a framework for developing and assessing future leaders around the world. It defines the leadership behaviors we value in employees at all levels. Our greatest potential is realized when we help employees realize their greatest potential. To help cultivate the leadership capabilities of every individual, we continually assess our talent management processes, tools, and leadership effectiveness. Johnson Johnson is committed to developing the talents and skills of our employees in order to position them to solve the health care needs of the future. [pic][pic][pic][pic][pic][pic][pic][pic][pic][pic][pic][pic][pic][pic][pic][pic][pic][pic][pic][pic][pic][pic][pic][pic][pic][pic][pic] How to cite Introduction of Johnson Johnson, Papers

Means To Tragic Ends (oedipus Essay Example For Students

Means To Tragic Ends (oedipus Essay Does man really have free will, or does free will lie within a system of limitations that gradually compose a web of circumstantial fate that ultimately cannot be torn apart? The events in both Oedipus The King and Antigone controversially suggests that man ultimately chooses his own deeds and endures fate and the responsibilities for them. These events brought by fate are unmistakably aggravated by certain characteristics within the characters. Oedipus, from Oedipus The King, Antigone, and Creon, both from Antigone possess such flawed characteristics that lead to their tragic ends. Oedipus possesses a multitude of characteristics, some of them common to other characters, but pride is exceptionally prevalent. This characteristic, which margins withutter arrogance, appears to be one of the dominant flaws that causes Oedipus tragic downfall. This is plainly established in the beginning of the play in which he states I Oedipus whom all men call the great.; (p11.8). This is strengthened by the Priests replies of Oedipus, Greatest in all mens eyes,; (p12.40) and Noblest of men; (p12.46). However, pride is not the only characteristic which contributes to Oedipus tragic end. There exists his temper, which is initially presented in the argument between Teiresias and himself. After Teiresias speaks the truth as factual, Oedipus replies Do you imagine you can always talk like this, and live to laugh at it hereafter?; (p26.367) and then soon after calls Teiresias a fool; (p29.433). His temper is also exposed whenhe threatens to banish or kill Creon after Creons attempted reasoning. Another contributing factor is his suspicion for others, this is evident where he questions Teiresias Was this your own design or Creons?; (p.27.377). He is falsely rationalizing that Teiresias is secretly plotting, in coalition with Creon, to overthrow him. Moreover, Oedipus has an unrelenting pursuit for the truth, which is demonstrated when he finally believes that he is the murderer and that Polybus was not his father. Nonetheless, he continues with his search with an extensive questioning o f both his wife Jocasta and the messenger. Furthermore, Oedipus exhibits self-loathing and a desperation towards the end of the play. After the facts have been voiced, he desperately attempts to rationalize the evidence and states, You said that he spoke of highway robbers who killed Laius. Now if he uses the same number, it was not I who killed him. One man cannot be the same as many. But if he speaks of a man travelling alone, then clearly the burden of the guilt inclines towards me.; (p47.842). At the end of the play, after all has been revealed, Oedipus expresses self-loathing as he whimpers Now I am godless and child of impurity, begetter in the same seed that created my wretched self. If there is any ill worse than ill, that is the lot of Oedipus.; (p69.1360). Although not as potent as her father Oedipus, Antigone also holds a detrimental sense of pride. This is presented in the speech between Creon and herself, How can such as I, that live among such troubles, not find a profit in death?; (p178.507). An additional contributing element to Antigones tragic end is her acceptance and welcoming of death, which is evident when she states, Life was your choice, and death was mine.; (p183.610). Creon affirms this by declaring In that place she shall call on Hades, god of death, in her prayers.; (p192.844). Furthermore, Antigone appears to display righteousness when she states But if Creon and his people are the wrongdoers let their suffering be no worse than the injustice they are meting out to me.; (p196.984). .u398b63ed3ec9255b629c1e457249cff6 , .u398b63ed3ec9255b629c1e457249cff6 .postImageUrl , .u398b63ed3ec9255b629c1e457249cff6 .centered-text-area { min-height: 80px; position: relative; } .u398b63ed3ec9255b629c1e457249cff6 , .u398b63ed3ec9255b629c1e457249cff6:hover , .u398b63ed3ec9255b629c1e457249cff6:visited , .u398b63ed3ec9255b629c1e457249cff6:active { border:0!important; } .u398b63ed3ec9255b629c1e457249cff6 .clearfix:after { content: ""; display: table; clear: both; } .u398b63ed3ec9255b629c1e457249cff6 { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .u398b63ed3ec9255b629c1e457249cff6:active , .u398b63ed3ec9255b629c1e457249cff6:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .u398b63ed3ec9255b629c1e457249cff6 .centered-text-area { width: 100%; position: relative ; } .u398b63ed3ec9255b629c1e457249cff6 .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .u398b63ed3ec9255b629c1e457249cff6 .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .u398b63ed3ec9255b629c1e457249cff6 .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .u398b63ed3ec9255b629c1e457249cff6:hover .ctaButton { background-color: #34495E!important; } .u398b63ed3ec9255b629c1e457249cff6 .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .u398b63ed3ec9255b629c1e457249cff6 .u398b63ed3ec9255b629c1e457249cff6-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .u398b63ed3ec9255b629c1e457249cff6:after { content: ""; display: block; clear: both; } READ: What Is True Love? EssayNot unlike Oedipus once was, Creon was also a proud ruler. In a confrontation with Antigone he states, When I am alive no woman shall rule.; (p181.579), which suggests that his pride is adamant and unforgiving, more so than Oedipus. Creon also exhibits stubbornness along with his pride, this is evident when he states My enemy is still my enemy, even in death.; (p181.575). His pride becomes even stronger when others attempt to defy his will. His argument with his son Haemon demonstrates this where he states, let it be from a man; we must not let people say that a woman beat us.; (p187.733) and when he asks Should the city tell me how I am to rule the m?; (p189.794). The flawed characteristics held by both Oedipus and Antigone that lead to their tragic ends are ironically contradictory. The probable foremost characteristic flaws of Oedipus is his inability to see the situation he has placed himself in, and that he intentionally ignores the hints and prophesies that everyone else knows. Antigones feasibly leading characteristic flaw is her expectation of pity for the wretched situation she was born into. In opposition with Oedipus, whereas he does not want or expect pity from those around him partially because he does not realize his calamitous situation. The flawed characteristics of father and daughter are similar to the sides of a coin. On one side, Oedipus is caught in the center of a disastrous situation ignorant to the world around him. However, on the other side of the coin, Antigone is fully aware of the impure situation she was born into. Unlike her father, Antigone wants people to know about her deplorable position so they can show sympa thy for her. The strengths of her father Oedipus, have become her weaknesses, and the strengths of his daughter Antigone, are Oedipus weaknesses. Creons flawed characteristic is undoubtedly his pride. A sense of pride as strong as a lion, yet as fragile as a small bird, added with his stubbornness and temper, created a man as unmovable as a mountain. This flawed characteristic prevented him from heeding to the advice of others, primarily his son, and lead to the destruction of all that he held close. Ultimately, Oedipus is guilty in the end, not for killing his father and marrying his mother, rather it is his attempt to raise himself above others, disregarding the facts and wisdom brought to him. Antigone, a woman of nobility and idealism, is guilty of the immature masochistic desire to martyr herself. Creons guilt, perhaps the most chosen, is his inability to recognize that someone other than himself can be right. These characteristics are fated by man, not by fate itself, and created a web of circumstantial fate. The events brought on by these characters could have been avoided if thecharacteristics were not part of their identities. Thus, it is the characteristics within the character that determines their fate, not fate which determines their character.

Benetton Group evolution of Communication Strategy Essay Example

Benetton Group: evolution of Communication Strategy Essay 1. An effective advertising campaign needs to have an audience and a purpose. The direct objective of most advertising is to convey a specific message to a specific audience; the ultimate objective is almost always to induce consumers to buy something. Often, the sales objective is achieved through stages, such as making the consumer aware of the brand or product, leading the consumer to like our brand or product and eventually leading the consumer to trust the brand or product. Furthermore, an advertising campaign might be directly simply towards enhancing the brand or company image. Benetton advertising campaign revolves around promoting the company as a life style brand. They campaign focuses on social and political issues like racial integration, AIDS awareness, war poverty, child labor, death and pollution. They want to build a social conscience in the community, on the other hand transmitting that Benetton is an active member in promoting freedom by being pro-life. 2. At first, their awareness campaign succeeded in raising the brands profile, but the strategy towards the depicting of strong shocking images, especially with the introduction of reality advertising (1992), eventually caused dissatisfaction among customers, retailers, government bodies and various international non-profit organization. We will write a custom essay sample on Benetton Group: evolution of Communication Strategy specifically for you for only $16.38 $13.9/page Order now We will write a custom essay sample on Benetton Group: evolution of Communication Strategy specifically for you FOR ONLY $16.38 $13.9/page Hire Writer We will write a custom essay sample on Benetton Group: evolution of Communication Strategy specifically for you FOR ONLY $16.38 $13.9/page Hire Writer Not withstanding that, Benetton managed to enhance credibility among its customers. Customers were getting the message that the company is venturing towards these social issues because it truly believes in its spirit to contribute to society injustices. Furthermore, their advertising was not like traditional adverting whereby the company, quoting Toscani, shows you a fictitious reality in which you will be irresistible if you make use of our products. Their reality concept meant also to enhance the brand image of manufacturing genuinely good products. 3. I agree that offensive images in the world of art and journalism are more acceptable than in advertising. If one had to analyze most of DGs Adverts, they are representing Napoleonic art with a futuristic conception. Most of these adverts have been subject of controversy regarding the dehumanization of the women. Is there a difference between the 17th Century rape art and the DG Gang rape advert? Can one claim that they are both artistic? If yes, why is the DG ad considered to be offensive? Maybe because its an advert! 4. Peta used shocking advertising by showing celebrity Shirley Manson holding a skinned animal ( here is the rest of the coat) while Humans for Animals depicted beheaded man or dead babies being tortured by animals with the message Dont treat others the way you dont want to be treated Shocking adverting can be used by organizations who want to create social and environmental awareness such as Greenpeace, drugs awareness campaigners and addiction prevention centers. From the example above animal right movements might only employ effectively shocking advertising. 5. I believe that shocking advertising most often repel the audience. In addition, these adverts might distort the customers from the main objectives of purchasing the brand. At subconscious level they might associate Benetton more with their human right campaign than with the products they actually offer. The use of conventional advertising will assist the company gaining back some of the brand reputation. Through the use of conventional advertising they can still transmit the core notions of peace and unity, which are their strong points, without risking to negatively influencing their audience. Such a strategy would still make them innovative.

The Value of Apple Certification

The Value of Apple Certification Apple certification is something not many people even know is available. One reason is that Macs are still not nearly as popular as Microsoft Windows in the corporate world. Still, it does have a specific niche in business. Creative organizations like advertising agencies and media outlets like newspapers, magazines, and video production facilities normally rely much more heavily on Macs than other businesses. In addition, a number of school districts nationwide are Mac based. And most large companies have a few Macs scattered around, especially in corporate art and video departments. That’s why it can make sense to get an Apple certification. Although not nearly as numerous as, for example, Microsoft certified individuals, Mac certified pros are valuable in the right setting. Application Certifications There are basically two certification paths for Apple: application-oriented and support/troubleshooting-oriented. Apple Certified Pros have expertise in particular programs, like the Final Cut Studio video editing suite or DVD Studio Pro for DVD authoring. For certain applications, like Logic Studio and Final Cut Studio, there are several levels of training, including the Master Pro and Master Trainer credentials. These can be handy to have if you’re self-employed and do contract video editing work, for example. If teaching is your thing, consider becoming an Apple Certified Trainer. The chief benefit of a certification like this would be for instructors and trainers working with students learning the programs. Technology Certifications Apple also offers a number of titles for the more â€Å"geeky† folks. Those who like computer networking and digging into the guts of an operating system are targeted here. There are three Mac OS X certifications offered, including: Apple Certified Support Professional (ACSP). This is an entry-level credential for support personnel, equivalent to the MCP. It covers the Mac OS X client, but not Mac OS X server.Apple Certified Technical Coordinator (ACTC). The next level adds Mac OS X server support and is geared toward entry-level system administrators working on smaller networks.Apple Certified System Administrator (ACSA). This is for high-end Mac system administrators, working in complex and often large environments. You should have several years experience working with and administering, Mac networks before attempting this one. Apple also has credentials for hardware and storage specialists. Apple’s storage device is called Xsan and offers two titles for experts in this area: Xsan Administrator and the Apple Certiï ¬ ed Media Administrator (ACMA). The ACMA is more technical than Xsan Administrator, involving storage architecture and networking duties. On the hardware side, consider becoming an Apple Certified Macintosh Technician (ACMT) Certification. ACMTs spend a lot of their time pulling apart and putting back together desktop machines, laptops, and servers. It’s the Apple version of the A credential from CompTIA. Worth the Money? So, given the range of Apple certifications available, the question is whether they’re worth spending the time and money to achieve since there are far fewer Macs in business use than PCs? One blog by an Apple fan asked that question and got some interesting answers. â€Å"The certifications are very useful and are valid industry recognised accreditation. Im pretty sure that a having Apple accreditation on my CV helped me get my current job,† said one Apple Certified Pro. Another compared the Apple certifications and Microsoft: â€Å"As for Apple vs Microsoft... MCSEs are a dime a dozen. Any Apple Cert is rare and if you have both (like I do) it is very marketable and valuable to clients. Scarcity is key to being valuable and my business in the past 18 months has exploded due to Apple and our requirement for dual certs.† One multiple-certification Mac expert had this to say: â€Å"The certifications definitely help, when it comes to showing prospective clients (and even future employers) that you know Macs.† Additionally, this article from Certification Magazine discusses how one college is starting to turn out Apple-certified students who are finding work, in part thanks to the credential. Judging from those responses, it’s safe to say that Apple certification is quite valuable in the proper situation.

Discuss the practical steps a university may take to help its students Essay - 1

Discuss the practical steps a university may take to help its students be as competitive as possible when they enter the labour market - Essay Example (Farazmand and Pinkowski 2007, p. 183) In this regard, this paper will outline important steps that the universities and colleges could undertake in order for its students to be competitive in the labor market. These steps would be cited in the context of two important roles that the school is thought to play. The university, wrote Achuthan (1993), in its functionalist role, is seen as one of the final steps in the educational system, completing the long preparation of the student for his or her role in society. (Achuthan p. 27) The tertiary educational institution, hence, must ensure that their students have been immersed and ingested the basic stock of knowledge that represents the core values of its culture. Here, it is emphasized that the student is not just educated but that he or she would leave the school armed with specific employment-oriented skills and knowledge. Education institutions can do this by coordinating with the government and the private sector. Such initiative could provide the school with the knowledge and tools in order integrate in its curriculum those skill and knowledge areas that are demanded by industries today. This is demonstrated, for instance, in the way the Singaporean education system works. The fundamental characteristic of the Singaporean system is the involvement of the government in the creation of curricula in the universities. This is shown in the existence of the state agency called Economic Development Board (EDB), which is concerned with the general responsibility of ensuring the inward investment in the country. Part of its mandate is to assure the human resource requirements for new industries to be created by the foreign capital. EDB ensures that education and training system is capable of producing the right type of skills required for the new industries, as part of the greater strategy to lure

Business law Essay Example | Topics and Well Written Essays - 1500 words - 7

Business law - Essay Example Moreover, her offer was published in a local newspaper, read by a large group of persons. Cheryl’s offer is unilateral as she â€Å"promised† in her advertisement to sell her minibuses to anyone who will pay  £15,000. Therefore, Cheryl made a legal conditional promise. On the other hand, there is the possibility, as it happened in Cheryl’s case, that more than one person will become interested in her offer and will be willing to accept it. Thus, it is necessary to clarify, judging by each person’s actions, who has the right to enter into a contract with Cheryl. The general rule of acceptance of an offer resulted from the case of Holwell Securities V Hughes 1974, where it was stated that the acceptance of one’s offer must be communicated to the offeror by the person that is accepting the offer in any possible way. Of course, the manifestation of the acceptance must be exteriorized, so that it is understood by the offeror. Moreover, the manifestation of accepting the offer must be linked to the offer itself and the offeror must receive the acceptance. There are several manners of accepting an offer: in written form, orally or by mail. In order to understand if Cheryl has a contract with any of the accepting parties, their manners of acceptance must be analyzed. The first person – Britney – told Cheryl she would let her know within the following week whether or not she would purchase the minibuses. The following week Britney accepted the purchase price of the black minibuses for  £15,000 by speaking to Cheryl directly. In the meantime, Cheryl made an offer via an e-mail for a reduced price of  £12,000 to her friend Amy, who agrees to purchase the minibuses on the condition that they are re-sprayed white. So, Amy made a cross offer, stating that she would accept Cheryl’s offer if this condition was respected. In the case of Tinn v Hoffmann & Co (1873) 29 LT 271 it was shown that cross offers do not lead to a binding

The Impact of Social Media and Viral Marketing on the Film Industry Essay

The Impact of Social Media and Viral Marketing on the Film Industry - Essay Example Different network websites focus on different issues which include books, general, film, music, community, health, education and tourism. A Marketing technique similar to a self-replicating virus through an internet, using social networking or other internet applications for creating or increasing brand value is called as viral marketing. According to St-Amant (2012 p. 1), a patient principal uses viral marketing for stronger results. This paper seeks to analyse and make recommendations as to how the managers of the film industry can respond to the issues relating to social media and viral marketing considering their impacts on the industry with justification for recommendations. Evolution of social media over a period of time indicates how businesses have made use of it for marketing. Understanding the developments taken place in social media is important for evaluating its impact and reorienting our strategies in line with technological changes. Evolution of social media Once, word of mouth was the greatest marketing mantra. Also, rumour gets thicker as it spreads. In social media, it can become a mania or rage due to viral power in self-replicating techniques, if the strategy is logical and sound. According to Hinz et al (2012 p. 12) ‘hubs and bridges are key to the diffusion of viral marketing campaigns.’ Social media has broken the concept of ‘time’ in marketing perspective. Time and place are no longer the prohibiting factors in viral marketing in social media. The Web 2.0 phenomenon made collaboration with the customers easier.... 12) ‘hubs and bridges are key to the diffusion of viral marketing campaigns.’ Social media has broken the concept of ‘time’ in marketing perspective. Time and place are no longer the prohibiting factors in viral marketing in social media. The Web 2.0 phenomenon made collaboration with the customers easier. A single new contact brings all of its other contacts to the business in viral marketing that could be compared with infection through a web of the network with endless permutations and combinations. ‘Going viral is like a calculus function mixed with the element of randomness – Brad Hines.’ (Torkildson, 2012) Viral marketing’s impact on brand or content propagated in social media can be positive or negative. The absence of copy rights or patent laws for the contents propagated in social media attracts people and viewership is encouraged. Monetisation of viewership becomes easier where there is surge in demand for content. The Ou tdated brand of Old Spice has been revived by P&G in their viral marketing strategy for the product. The Responses to the Old Spice marketing strategy ‘topped 6 million total views and 60 000 Tweets in the first 24 hours on YouTube’ (Mills, 2012 p. 165) Similarly, negative impact affects the business severely. In a way, it increases the level of corporate social responsibility among the companies as the customers’ views on corporate practices converge at a faster pace that forces the companies to review their strategies more in line with public expectations. ‘Greenpeace supporters were so successful at flooding Nestle's Facebook page last year that the Kit Kat maker's social media rep publicly lashed out’ (CNN Money, 2011). Social media is an evolving theme with a very short history. Releasing

Mechanisms Of Conservative And Replicative Transposition Biology Essay

Mechanisms Of Conservative And Replicative Transposition Biology Essay Bacteriophage Mu is a temperate phage which adopts transposition pathway in its life cycle. Mu has the capability to integrate into numerous sites in host Escherichia coli genome and cause mutations due to its insertional activation. Mu transposes via two major pathways; conservative and replicative transposition though the molecular switch between the two mechanisms remain unknown. This review will focus on the comparisons between replicative and conservative transposition. The first part will discuss the similarities between the two mechanisms; donor DNA cleavage step and strand transfer step which involves nucleophilic attacks, generating single-strand nicks in Mu DNA and joining it to target DNA via one-step transesterification mechanism. The latter part will concentrate on the different characteristics in each transposition mechanism; in replicative transposition, the end product is duplication of transposon copy in both target and host DNA while in conservative transposition, a simple insertion of transposon is produced in the target DNA. 1. Characteristics of bacteriophage Mu Phage, derived from the Greek word phagein, literally means to eat. Bacteriophage Mu was named as such(find out who did) due its nature of infecting and inducing high levels of mutation in host bacteria Escherichia coli., hence the name Mu for mutator. The dual nature of Mu transposon and virus has made it as the archetypal model of studying phage genetics. Bacteriophage Mu is a temperate phage of E. coli which employs the transposition mechanism in its life cycle. Transposition can either be conservative (excising the transposon and inserting it into bacterial chromosome) or replicative (transposon copies are produced in both transposon and bacterial chromosome). Both mechanisms will be discussed extensively later in this article. Unlike the phage ÃŽÂ », insertion of Mu genome into the target site proceeds in a randomly manner which makes it an excellent mutator. Fig. 1: The life cycle of bacteriophage Mu(5). The life cycle of phage Mu is shown schematically in Fig. 1 above. Bacteriophage Mu infect susceptible host cell by adsorption and then, injects its linear viral genome. Once inside the host cell, the linear genome does not circularized(4,5,19), unlike in phage ÃŽÂ ». In either case of lytic or lysogenic phase, Mu integrates its DNA into the host genome via conservative transposition(16,19). This is observed differently in phage ÃŽÂ » where the infecting phage DNA will be integrated into host genome only during lysogenization(19). An enzyme called transposase, encoded by MuA gene in the phage genome, is absolutely crucial to carry out this conservative transposition step. Phage DNA is inserted at multiple sites in a bacterial genome which lead to the assumption that the insertion occur by a random manner(8). However, there are several factors that influence target site selection such as MuA protein efficiency and transposition immunity(15). After integration, Mu usually adopts a quiescent prophage lifestyle(lysogenic phase). The preference between lysogenic and lytic phase in Mu life cycle is dependent on its stability in the lysogen and lysogenic repressors. However, lysogens of Mu phage sometimes enter the lytic phase though this is a rare event. When induced, usually by using temperature-sensitive repressor mutants of phage Mu and subject it at 42ËÅ ¡C, the lysogen will enter lytic cycle. When the lysogenic repressor is inactivated, Mu transposes via replicative transposition, producing copies of phage genome which will be packaged into new virions. The virions then lyse the host cell and infect new hosts. Bacteriophage Mu virions comprised of icosahedral head(diameter 54nm), a baseplate, a contractile tail and six short tail fibres(5). Fig. 2: Simplified cartoon illustrating packaging of Mu genome. Typical length of phage Mu DNA is approximately 37kb long. Additional 2 kb of host DNA is incorporated during DNA packaging which is shown as flanking each end of the integrated Mu genome, with most of it at the right end. Unique sequences of host DNA and at the right end of the packaged DNA is dependent on initiation site of packaging in the host DNA(24). Fig. 3: Physical and genetic map of bacteriophage Mu. Solid black lines represent Mu DNA while the boxes at the two ends indicate flanking host DNA sequences. Mu genes (indicated in block letters) and their corresponding translational products are as indicated(19). A typical size of wild-type phage Mu DNA is about 37.5 kb, however each phage capsid can accommodate up to 39 kb long. Phage genome has a pac site which serves as the starting point in packaging of the phage DNA, located within attL(5). The initiation cleavage by phage enzyme terminase occurs upstream of the phage pac site, which includes host sequence of about 50-150bp flanking the left end. Second cleavage initiated when a complete filling of capsid is achieved, which includes 0.5 kb to 2 kb of host sequence flanking the right end(1). Genetic and physical map of phage Mu is illustrated in Fig. 3. Bacteriophage Mu utilizes headful mechanism strategy, which confer variable lengths of host DNA flanking the left ends of Mu DNA depending on the initiation site of genome packaging(Fig. 2). 2. Transposition mechanism (E) (D) (C) (B) (A) Fig. 4: Modes of bacteriophage Mu transposition. (A), (B) and (C) are the common steps in both conservative and replicative transposition of phage Mu. In conservative and replicative transposition, phage Mu will follow-up step (D) and (E) respectively. Curved arrows indicate nucleophile attack, transferring the 3-OH ends to the staggered 5-phosphate ends of target DNA. Dentate lines (XXXX) indicate target DNA sequences which are duplicated during transposition (16). Numerous in vitro studies have been conducted to study the mechanism of transposition, and usually mini-Mu elements are used. A minimal Mu element consists of a selectable gene, a plasmid replication origin and essential Mu ends(2). The mechanism of transposition is discussed in respect to an in vitro system from this point onwards unless stated otherwise. Following discussion on transposition mechanism are based on Shapiro model(22) as it has been widely accepted as the golden model in this field. The current known modes of transposition is divided into two: non-replicative (conservative) and replicative transposition. Both strategies utilize the same mechanism up to point (Fig. 4C) where each strategy employs different mechanism, producing different end products. A simple insertion of transposon is generated in target DNA by conservative transposition (Fig. 4D) while two copies of transposon formed in both donor and target DNA by replicative transposition (Fig. 4E). Point A to C are considered as the similar features in both conservative and replicative transposition while point D and E is the distinction between the two modes of transposition. Therefore, mechanisms involved in point A,B and C are discussed in context of both replicative and conservative transposition, which comprises of DNA cleavage step and strand transfer step. Sequential stages of both cleavage and strand transfer steps are illustrated in Fig. 4. 2.1 Donor DNA cleavage step Two critical chemical steps in both transposition pathways are donor DNA cleavage step and DNA strand transfer step(5,8). The donor DNA cleavage step is initiated when water molecules within an active site act as nucleophiles, and attack phosphodiester bond in DNA backbone at each of the transposon end(4,5). The cleavage step involves a direct hydrolysis of phosphodiester bond by water, and not by covalent enzyme-DNA intermediate(17). The phosphodiester bond is cleaved at the flanking host-transposon DNA boundary. 3-hydroxyl (OH) ends of the Mu DNA are exposed at the end of the cleavage step. Strand transfer results in fusion of target and donor DNA, which forms an intermediate molecule (8). The process (simplified in Fig. 4C) follows the Shapiro model(22). Bacteriophage-encoded proteins, MuA protein (transposase) and MuB protein (ATPase) are required for transposition. Other requirements to ensure efficiency of transposition are accessory proteins such as host-encoded DNA bending proteins called hydroxyurea (HU) and integration host factor (IHF)(8). The inverted repeats at the end of donor DNA, and target sequence on bacterial chromosome are also important in transposition mechanism. The assembly of higher order protein-DNA complexes called transposome has been identified by in vitro studies(6). A three-site synaptic complex called the LER complex comprising right and left ends of Mu and transpositional enhancer, was formed in the beginning of transposition in vitro(23). MuA protein binds to MuA binding site at the ends of Mu DNA as monomer, and subsequently function as tetramer of MuA (transposase). Host IHF and HU protein were found to aid in formation and stabilisation of LER complex. The LER complex is relatively unstable and so, is rapidly converted into stable synaptic complex (SSC), also known as type 0 complex(17). This is the critical checkpoint before any chemical reaction is carried out as it is the rate-limiting step of cleavage reaction(6). A stable synapse between tetramer of MuA and the two ends of Mu DNA is made but no cleavage is initiated yet at this point. Nonetheless, the active site is structurally occupied to the region around the scissile phosphate while the flanking DNA are destabilized upon formation of the SSC complex(6). In addition to formation of a stable synapse, the Mu ends needs to be properly-oriented, a super coiled DNA topology, and accessory DNA sites are also important to proceed to the next step. Formation of SSC usually is short-lived in presence of Mg2+ but can be accumulated in presence of suitable divalent cations such as Ca2+,which promotes the formation of SSC(8,17). Next, SSC is converted into a type 1 transposome complex, also called as cleaved donor complex(CDC)(9). The 3 ends of Mu DNA are nicked in presence of Mg2+. Two subunits of MuA tetramer, that are associated with the sites that undergo cleavage, assemble in trans arrangement which favours the strand transfer reaction(5). The formation of CDC can then be thought as the result of donor DNA cleavage step. Type 1 transposome complex exhibits greater stability than the type 0 complex though MuA forms structural and functional core in both transposome complexes(6). In addition of stably bound tetramer of MuA proteins, there are loosely associated MuA proteins present in the CDC as well. In absence of MuB protein, MuA tetramer is unable to promote strand transfer reaction unless these extra MuA proteins are present. MuB protein is an ATP-dependent DNA-binding protein, which also acts as an allosteric activator of Mu transposase (MuA proteins)(21). Transposition can still proceed in absence o f MuB proteins, but MuA protein by itself is only 1% efficient(3). 2.2 Strand transfer step A hallmark of this step is the formation of strand transfer complex (STC), also known as type 2 transposome complex. The end product of STC is formation of a branched molecule(Shapiro intermediate) which is characterized by a covalent interaction between donor DNA and target DNA via 5bp single-stranded gaps and its ÃŽÂ ¸ structure(22). MuB protein first captures a target molecule and bring it to the vicinity of the transposome complex, forming a TC complex(6). Formation of TC complexes rapidly undergo one-step transesterification reaction, which is the rate-limiting step in the strand transfer step. Interestingly, recruiting of target molecules by MuB proteins and formation of TC complexes can occur at several time point during the reaction pathway(6). This is a particularly efficient step to maximize transposition potential as it would speed up rate of strand transfers during transposition. The free 3-OH ends produced from the cleavage step act as nucleophile and attack phosphates of target DNA at the 5 ends. 5-nucleotides long offset nicks are made in the target DNA, generating a staggered arrangement(3). At this stage, the MuA proteins(transposase) are still tightly bound to the branched molecule with single stranded gaps. This pose an obstruction for the assembly of replication fork by host replication factors. The structure of the branched molecule is simplified in (C) of Fig. 4. The forming of this intermediate molecule serves as the critical point which distinguish between conservative and replicative transposition. A widely accepted model is that the resolving of this co-integrate molecule by a special resolvase complex leads to double copies of transposon being made in both donor and target site(REFerence). This is by definition, a replicative transposition pathway. Thus, the strand transfer complex is destabilized and disassembled by a system of eight E. coli host molecular proteins (DnaB helicase, DnaC protein, DnaG primase, DNA polymerase II, single-strand binding protein, DNA gyrase, DNA polymerase I and DNA ligase) and molecular chaperon called ClpX, producing cointegrates(13). This transition from transposome complex to a replisome results in duplication of 5-bp target DNA sequences flanking both ends of Mu DNA. Alternatively, if the bacteriophage Mu is to enter the conservative pathway, the co-integrate molecule is repaired or processed without performing Mu DNA replication. The end product of STC in a conservative transposition is a simple insertion of single mini-Mu element inserted into the target DNA(8). However, the mechanism of this model is poorly understood. Fig. 5: Transposome complexes involved during DNA cleavage complex and DNA strand transfer. (A) A plasmid (gray line) bearing donor mini-Mu element (black line) DNA in the in vitro system is negatively coiled. (B) In presence of host HU protein, Mu A protein bind to the two ends of Mu DNA forming a stable synaptic complex (not shown). Assembly of MuA tetramer produces a nick at each ends of Mu DNA, creating a cleaved donor complex (CDC). (C) Nicked 3 ends of Mu DNA are joined together to target DNA in presence of MuB protein forming a strand transfer complex (STC). MuA tetramer is still tightly bound to the Mu ends in the STC. (D) In replicative transposition, a cointegrate molecule is produced when replication of target DNA initiated from the 3 Mu ends by host replication machinery (13). 3. Replicative transposition Replicative transposition was first suggested by Ljungquist and Bukhari (1977) to occur in situ after induction of lysogens, which means that the Mu prophage was not excised from host chromosome during transposition(14). The lysogens were digested with restriction enzymes which cleaves both host and Mu DNA at specific restriction sites. Two of the fragments from the restriction digests contain both host and Mu DNA, which corresponds to junctions between host and prophage DNA, suggesting that prophage DNA is replicated in situ of host chromosome(19). Several genetic and biochemical predictions made in the Shapiro model have been demonstrated in both in vivo and in vitro studies, hence this model is accepted as a plausible mechanism to explain transposition in phage Mu. Numerous techniques have been done to study the direction of replication of Mu DNA during transposition. Results obtained by annealing of Okazaki fragments to separated strands of Mu DNA shows that more than 80% of Mu molecules replication proceed from left to right end(11,19). Electron microscopical observation of mini-Mu element shows that replicating molecules in vitro replicate from both ends in equal probability'(11,19). Replication of Mu DNA is accepted to be predominantly unidirectional, that is from left towards the right end(20). Intramolecular replication pathway can result in inversion, deletion, and simple insertion while intermolecular events can produce co-integrate molecules(19). In the case of Mu transposition, formation of co-integrate molecule needs to be resolved in order to produce two replicons; one molecule contains transposon and target DNA while another molecule contains transposon and donor DNA(10). 4. Conservative transposition The main characteristic of conservative transposition is that phage DNA is not replicated prior to integration. Upon infection of a susceptible host cell (usually E. coli), Mu employs conservative, or also called non-replicative transposition to transfer its genome to the target site. As discussed earlier, conservative transposition pathway follows single strand nicks at the 3 ends of Mu DNA, of which the exposed 3-OH ends join to the staggered cut target DNA at the 5ends forming a co-integrate molecule. The co-integrate or so-called Shapiro intermediate is repaired and generates a simple insertion in the target DNA though the mechanism is still poorly understood. Shapiro model emphasized on single-stranded nicks at Mu ends, joining of Mu to a staggered double-strand break in target DNA, formation of an intermediate molecule, and shedding of heterogeneous of previous host DNA sequences after ligation in conservative pathway(22). On the other hand, Morisato and Kleckner (1984) proposed a different mechanism based on results with Tn10 transposition. Their model is double-stranded cleavages at the transposon ends generating an excised transposon, which then circularizes via ligation on one of the strands(18). It predicts shedding of host sequences from the Mu DNA ends before ligation into the new target DNA. Study of Mu transposition using plasmid substrates in vitro produced results in favour of the Shapiro model, and hence this model has been widely accepted and used in studies. Fig. 6: A model of conservative transposition which utilizes double-strand cleavages during integration. (A) Transposase bind to the inverted repeats at Mu-host boundary sites and cleaves off the transposon away. (B) Transposase made a staggered cut at target sequence of which exposed 3-OH ends of transposon attacks 5-phosphate ends of the host (not shown). The transposon then joins to the host sequence. Duplicated target sequence of 5-bp are completed by host replication machinery (7). The debate on single-strand or double-strand cleavage however does not end there. If phage Mu were to utilize the Shapiro model of transposition during integration (the well-established cointegrate mechanism), the flanking host sequences would remain bound to Mu ends. This would clearly pose a problem as subsequent target-primed replication of the linear integrant would not work, or simply break the chromosome(1). Evidently, results from in vitro experiments are against this as the transposition end products contain transposon, suggesting a complete transposition process have been accomplished. So, does the infecting Mu DNA utilize the Shapiro model where the cointegrate molecule gets processed and repaired, prior to replication at the flanking sequence? Or does it follow a cut-and-paste mechanism where both strands of Mu DNA gets cleaved off from the flanking host DNA sequence (as illustrated in Fig. 6), where no cointegrate molecule is generated, which eventually means, there is no need for resolve by replication? An in vitro experiment was done by Au et al. (2006) to observe the fate of flanking host DNA sequences upon phage Mu infection. Specific markers specific to the infecting phage Mu DNA as well as the donor host (lacZ/proB) were used. These markers were acquired from the host in which the phage had been propagated but absent in the host being infected(1). Upon infection of plasmids by bacteriophage Mu, signal for flanking sequences and Mu DNA were detected in the chromosome at the same time point (approximately at minute 8), which correspond to the integration time point of Mu. Subsequent expression of lacZ and proB were detected maximally at minute 15, significantly reduced at minute 30 and by minute 50, expression were halted(1). Maximal expression at minute 15 most likely corresponds to climax of integration of the infecting phage population. These findings strongly suggest that flanking sequences get integrated together with Mu DNA into the new target site and are subsequently, rem oved by a special mechanism(which explained the undetectable expression at minute 50). This then proves that infecting phage Mu employs an alternate cointegrate mechanism (also called as nick-join-process mechanism) in conservative transposition pathway, where the Mu DNA undergo single-strand nicks, joins to the target DNA, and repaired before replication of the 5-bp gap left by the flanking sequence(1). The mechanism of removal and repair of host flanking sequence however, remains ambiguous. Conclusion Dual nature of bacteriophage Mu, a transposable element and a virus, is certainly interesting but what is more fascinating is that it utilizes both replicative and non-replicative transposition throughout its life cycle. The former mechanism produces a transposon copy in both donor and target DNA while the latter usually generates a simple insertion of transposon in the target DNA, leaving a gap in the host DNA which most likely will get degraded. In the early stages, both replicative and conservative transposition pathway share a similar mechanism. Regardless of the transposition pathway, infecting Mu DNA during the first round of infection will integrate its DNA into the target chromosome via two critical steps; donor DNA cleavage step and strand transfer step. Mu uses a phosphoryl transfer involving nucleophilic attacks of water on phosphodiester bonds of Mu DNA, producing single-strand nicks. A second nucleophilic attack by exposed 3-ends of Mu DNA on 5-ends of target phosphodiester bonds, which then joins the Mu DNA to target DNA via one-step transesterification mechanism. A series of transposome complexes are formed throughout these processes including Mu-encoded MuA proteins(transposase) and MuB proteins(ATPase). A cointegrate is produced in both pathways but in replicative transposition, this intermediate molecule is resolved producing two replicons with transposon copy in each molecule. In conservative transposition, the cointegrate is repaired generating a simple insertion in the target DNA. Hence, it is more accurate to name conservative transposition as nick-join-process rather than the conventional cut-and-paste mechanism as the latter suggest double-strand nicks at the transposon end, which has been proven inaccurate by in vitro experiments. Both transposition pathways have been compared extensively in this review but much of functional core of the mechanisms remain to be understood. (2944 words)

Black Like Me: A Cultural Book Report :: Black Like Me Essays

John Howard Griffin was a journalist and a professional on race issues. After publication, he became a leading advocate in the Civil Rights Movement and did much to promote awareness of the racial situation sand pass legislature. He was middle aged and living in Mansfield, Texas at the time of publication in 1960. His desire to know if Southern whites were racist against the Negro population of the Deep South, or if they really judged people based on the individual's personality as they said. Because of this he felt that they had encouraged him to cross the color line and write Black Like Me. Plot:   Ã‚  Ã‚  Ã‚  Ã‚  Black Like Me is the story of a man named John Howard Griffin, who underwent a series of medical treatments to change his skin color temporarily to black; a transformation that was complete when John Howard Griffin shaved off his hair, and looking in the mirror, saw a bald, middle-aged black man. The reason he does this is for an experiment to see how racism was in the Deep South from personal experience. From November 6th to December 14th in the early 60's, he hitchhiked, walked, and rode through Mississippi, Alabama, Louisiana, and Georgia. After three weeks in the Deep South as a black man John Howard Griffin produced a journal covering his change into the black race, his travels and experiences in the South, the shift back into white society, and the reaction of those he knew prior his experience. The book was published and released. The reaction on the society differed in great ammounts. Characterization:   Ã‚  Ã‚  Ã‚  Ã‚  John Howard Griffin is the main character in the story. Throughout the story, this person displayed many qualities. He showed determination because he was bound and determined to become a black man so he could expose the truth about the Deep South and how racist they were. He also showed courage, for being able to pull through and do the things he did, such as become a whole new person of another race and going into dangerous territory where he knew he wasn't really welcomed. He also displayed a sense of dignity, because after he was done with this experiment, he was threatened several times and even burned in effigy in his hometown, but he still maintained his ground as long as he could. And last, but not least, he showed us a sense of hope, because no matter what, even in the darkest times, he would still keep at least a small bit of hope in him. Black Like Me: A Cultural Book Report :: Black Like Me Essays John Howard Griffin was a journalist and a professional on race issues. After publication, he became a leading advocate in the Civil Rights Movement and did much to promote awareness of the racial situation sand pass legislature. He was middle aged and living in Mansfield, Texas at the time of publication in 1960. His desire to know if Southern whites were racist against the Negro population of the Deep South, or if they really judged people based on the individual's personality as they said. Because of this he felt that they had encouraged him to cross the color line and write Black Like Me. Plot:   Ã‚  Ã‚  Ã‚  Ã‚  Black Like Me is the story of a man named John Howard Griffin, who underwent a series of medical treatments to change his skin color temporarily to black; a transformation that was complete when John Howard Griffin shaved off his hair, and looking in the mirror, saw a bald, middle-aged black man. The reason he does this is for an experiment to see how racism was in the Deep South from personal experience. From November 6th to December 14th in the early 60's, he hitchhiked, walked, and rode through Mississippi, Alabama, Louisiana, and Georgia. After three weeks in the Deep South as a black man John Howard Griffin produced a journal covering his change into the black race, his travels and experiences in the South, the shift back into white society, and the reaction of those he knew prior his experience. The book was published and released. The reaction on the society differed in great ammounts. Characterization:   Ã‚  Ã‚  Ã‚  Ã‚  John Howard Griffin is the main character in the story. Throughout the story, this person displayed many qualities. He showed determination because he was bound and determined to become a black man so he could expose the truth about the Deep South and how racist they were. He also showed courage, for being able to pull through and do the things he did, such as become a whole new person of another race and going into dangerous territory where he knew he wasn't really welcomed. He also displayed a sense of dignity, because after he was done with this experiment, he was threatened several times and even burned in effigy in his hometown, but he still maintained his ground as long as he could. And last, but not least, he showed us a sense of hope, because no matter what, even in the darkest times, he would still keep at least a small bit of hope in him.

Is the Panama Canal Sustainable?

The Panama Canal was completed in 1914 by the United States. The 51 mile long route cuts through Panama at the narrowest point between North and South America to connect the Atlantic and the Pacific oceans. Panama is in Central America between Columbia and Costa Rica. The Panama Canal The canal was built to and save ships from Europe and Africa going the entire way around the bottom tip of South America (the red route on the map), to reach western Asia. The canal cuts through Panama and allows most ships to pass through it so save on cost and time (the green route on the map). By building this canal, shipping has been given an enormous advantage, as ships no longer have to sail around the tip of South America to reach either ocean and sailing time is drastically reduced. Investigating the natural environment The climate in Panama is hot and humid, with a prolonged rainy season (May to January) and a short dry season (January to May). The region's normal daily temperature is 26 degrees Celsius and varies little throughout the year, perhaps 2-3 degrees. During the evening hours, however, the temperatures change more considerably, and can fluctuate as much as 6-10 degrees Celsius. There is a climate graph below showing the climatic conditions in Panama. Climate, rainfall and humidity graphs for Panama This graph shows that the rainy season does last from May to January and month with the highest rainfall in November with 569mm and the lowest rainfall in February with about 40mm of rain. This graph also shows that the average temperature throughout the year is around 26 degrees. There is very little seasonal variation in temperature but there are large seasonal fluctuations in rainfall. The humidity chart shows that the humidity is also high throughout the year, peaking between June and November, but only varying by 9% over the whole year. So between June and November, there is high humidity, high rainfall and on average, only 5 hours of sunshine a day as apposed to the 8 or 9 hours from January to April. A Sketch map of the panama region This map shows the rainforest and where the locks and the reservoirs are located. Man has had to create these reservoirs for the canal to function properly, meaning man has modified the drainage area. In order to make the reservoirs, much of the land has had to be flooded, rainforests and settlements also. This meant that many habitats were destroyed and many animals would have died as a result. Not only this, but substantial amounts of rainforest would have had to have been destroyed, that lay in the canal path and where the afore mentioned reservoirs are, again destroying habitats and killing animals. Along the route of the canal there is a series of 3 sets of locks that lower and raise the ships on their way to and from Atlantic and Pacific oceans. These locks are called the Gatun, Pedro Miguel and the Mira Flores locks. At Gatun there are 2 parallel sets of locks each consisting of 3 flights. This set of locks lift ships a total of 26 metres. The locks are constructed from concrete. More than 1.53 million cubic metres of concrete were used in the construction of the Gatun locks alone. The smallest set of locks along the Panama Canal are at Pedro Miguel and have one flight which raise or lower ships 10 metres. The Mira Flores locks have two flights with a combined lift or decent of 16.5 metres. Investigating the Social Environment Panama City is the largest city in panama. Its metropolitan area contains nearly one third of the nations inhabitants, about 1 million people. From 1980 to 1990 the city's population grew from 386,300 to 413,000. After 1990 the population again grew rapidly, increasing to 688,927. The city cannot cope with such rapid growth and there isn't enough accommodation for the whole population, so shantytowns start appearing, these are clusters of shacks, which the people build themselves. They make their ‘houses' out of anything they can find, corrugated iron, tyres and the like. These shantytowns accommodate only the poorest of the population as the richer citizens can afford the higher house prices in the city. This rapid urbanisation and the development of the shantytowns makes Panama City much more polluted. The shantytowns sprawl out from the City centre and start to intrude on the rainforests, then posing an ecological threat and threatening the sustainability of the Panama Canal. Urbanisation level This graph shows the percentage of urbanisation over the past 15 years and the predicted levels of the next 20 years. According to this graph urbanization is set to increase steadily over the next 25 years. The Panamanian government are moving people into the rainforest to give them a chance to rebuild lives and to escape the mass urbanisation and unhygienic conditions of the shantytowns. This relieves the congestion in the city and gives people new opportunities. Investigating the Economic Environment The Panama Canal is generating a lot of money for the people of Panama; it is not only a strong business and a power source, but a tourist attraction too. Many visitors come to visit the canal and bring a lot of revenue into the area, encouraging businesses to grow and prosper. The ships must pay over 15 hundred dollars to use the canal, so this brings a lot of revenue into the area. The Panama Canal can make the quality of life increase on one hand, but decrease on the other. The Canal brings a lot of revenue into the area although it can divide the social classes. The Canal creates a richer class, which are the people that profit from the canal, who continue to get richer as the canal brings in more and more money and a poorer class, as they have to move into the rainforest and live off the land with little or no money. It could also introduce crime into the area as the canal creates richer areas, with more valuable things in it, and with the poorer people living close by in the shantytowns, it is an open invitation for crime. If the Canal had to close, Panama would economically suffer immensely. Its main source of income would have dried up and the country's wealth would go down dramatically as a result. The shipping companies that use the canal would also suffer incalculably as their ships would have to sail around the tip of South America to reach the eastern world. Panama would have massive problems then with urbanisation, as people would flock to the city in hope of jobs, therefore the shantytowns will rapidly increase in size, posing new problems to the city. The Canal and it's reservoirs supply 700 000 people with fresh water. If the reservoirs cease to operate, then these people's water supply will be cut off. Evaluation If the Panamanian rainforest is cut down too much, the consequences will be dire. The canal will not be able to function properly as there will not be enough water in the reservoirs to sustain the canal. The tree's roots hold together the soil so if the trees are cut down during deforestation, then the soil becomes loose and with the huge amounts of rain that the area receives much of the soil will be washed away, into the reservoirs that feed the canal. If vast amounts of soil wash into the reservoirs then the soil occupies some of the volume of the reservoir, volume that could have been taken up by water. This means that the reservoirs cannot hold as much water as they were designed to hold. As the canal relies solely upon these reservoirs, depletion in the amount of water the reservoir could take would harm the canal's efficiency as every ship that travels through the canal takes with it an immense amount of water so there would not be the water available to work the canal, ultimately ensuring the closure of the waterway. Solutions The water in the lakes has been going down because of deforestation. The government have made a new â€Å"organic law† that allows the government to have the final say for any projects in the watershed zone. Three million dollars is being set aside to combat any environmental plans and satellite imaging is being set up so the government can view the area on a much larger scale and can see the real extent of the damage. This should enable the government to act quickly if they can see a potential threat. The Government must also regulate urbanisation as a spread of Panama City's unplanned, chaotic urbanization into the watershed would spell disaster for the canal, electricity supplies, and clean drinking water. However, the government are not perhaps taking the issue as seriously as they should be. In 1995, the government gave permission for a four-lane road to be built in the lower catchment of the watershed, ploughing straight through the national park. The Panama Canal can be sustainable if the correct precautions are taken to ensure that urbanisation and deforestation do not increase any more, otherwise, they will spiral out of control and the panama canal will have to close, ending many, many businesses in the local area and around the world.

Stalwart

Stalwart Stalwart Stalwart By Maeve Maddox A reader asks for clarification regarding the word stalwart: I am confused about the meaning of â€Å"stalwart† in the following context: â€Å"One of the most influential companies in high technology right now may be a 135-year-old industrial stalwart.† According to OED, as a noun, stalwart means â€Å"loyalist, hard-working supporter.† Nonetheless, I fail to grasp the meaning of stalwart qualified by industrial as adjective. As a noun, stalwart has more than one meaning; â€Å"loyal supporter† is only one of them. Stalwart began as an adjective. The Old English adjective stalworth was applied to things like ships to mean â€Å"serviceable.† When applied to people and animals, it meant, â€Å"strongly and stoutly built.† The meaning extended to include brave, courageous, and valiant. In Scots dialect, the word became stalwart and was reintroduced into English thanks to the popularity of the novels of Sir Walter Scott. In modern usage, stalwart functions as both adjective and noun. Adjective As an adjective, stalwart means, resolute, unbending, and determined, as well as brave, courageous, and valiant. For example: The epic valor of the Greeks in driving back the Italian invaders together with Britain’s stalwart resistance to Hitler’s crushing blows, has given new meaning to human courage in war. Her stalwart defense of the environment in Maryland is embodied in her support for building a green jobs workforce, protecting the Chesapeake Bay, and for a clean energy economy. Noun â€Å"A stalwart† can be a person who has achieved wide recognition in some business or pursuit: Hollywood stalwart Ernest Borgnine dies at age 95 Josh H. Groce, a  noted stalwart  of the Texas trial bar Or it can refer to a company or institution that has been in operation for a long time. This is the sense in which stalwart is used in the sentence submitted by the reader. Here are some more examples of this use of stalwart to refer to a company: Sales for the New York-based pharmaceutical stalwart  were $13.56 billion against last years $13.89 billion. The remaining companies experiencing growth last year [included] electronics retailer HHGregg Inc. and pharmaceutical stalwart Eli Lilly and Co. And while many of its architects are well-known Silicon Valley companies, longtime Milwaukee industrial stalwart Rockwell Automation Inc. has positioned itself at the heart of the phenomenon, which some consider the next industrial revolution. Finally, in the context of politics, the noun stalwart means, â€Å"a sturdy uncompromising partisan†: AIPAC lauds re-election of pro-Israel stalwarts First deficit panel picks are Democratic stalwarts Utah is overall a conservative state much in line with the public policy principles of Republican stalwarts like Gov. Mitt Romney, Gov. Michael Leavitt and Gov. Jon Huntsman.   Want to improve your English in five minutes a day? Get a subscription and start receiving our writing tips and exercises daily! Keep learning! Browse the Vocabulary category, check our popular posts, or choose a related post below:Masters Degree or Master's Degree?44 Resume Writing TipsPersonification vs. Anthropomorphism